This poster presents our findings on the impact of DL-a-aminoadipic acid (DLAAA) in inducing dose-dependent retinal neovascularization and macular edema in St. Kitts African green monkeys. It showcases the translational relevance of our models in replicating human retinal diseases, emphasizing the importance of precise dose metrics in preclinical research to optimize therapeutic strategies.

Our research details how different concentrations of DLAAA trigger varying severities of retinal damage, providing valuable insights into the progression and management of retinal diseases. This study is essential for preclinical researchers and drug developers, offering a robust framework to evaluate new treatments for retinal neovascular diseases by accurately simulating disease phenotypes and therapeutic responses.

In this scientific poster, you will learn more about:

• Insights into the dose-dependent effects of DLAAA on the progression of retinal neovascularization and macular edema in African green monkeys
• The importance of precise dosing in replicating human retinal disease phenotypes for effective preclinical evaluation of new treatments
• Methodologies for accurately simulating human retinal conditions using nonhuman primate models
• Applications of this research in informing the development of targeted therapies for retinal neovascular diseases

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