Pressure and time-dependent glaucomatous pathology in nonhuman primates with intraocular pressure elevation
This poster explores the dynamics of glaucomatous changes in the retina and optic nerve in response to elevated intraocular pressure (IOP) in African green monkeys. Our work plays a crucial role in preclinical research, particularly in modeling human glaucoma to improve the understanding and treatment of this complex eye disease.
The findings detailed in the poster are vital for the preclinical assessment of neuroprotective therapies for glaucoma. By illustrating how specific changes like retinal nerve fiber layer (RNFL) thinning and optic nerve head cupping correlate with IOP levels, we provide a foundational model for evaluating the efficacy of glaucoma treatments.
In this scientific poster, you will learn more about:
- Insights into the correlation between elevated intraocular pressure and the progression of glaucomatous changes in the retina and optic nerve
- Understanding the importance of preclinical models in studying human glaucoma and developing effective treatments
- Learn about the evaluation of neuroprotective therapies using robust preclinical models
- Implications for therapeutic development and the potential for personalized approaches in ocular health
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